UGT1A1*37 Reference Standard

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RQPA0018
FormatGenomic DNA
DescriptionUGT1A1, UDP-glucuronosyltransferase 1-1, is an enzyme that catalyzes the glucuronidation of substances to soluble metabolites for excretion (PMID: 28520360). Genetic polymorphisms in UGT1A1 may alter the metabolism of chemotherapy drugs such as irinotecan, resulting in severe toxicity.
  
Technical Data 
GeneUGT1A1
AA ChangeN/A
DNA ChangeN/A
Chr position (GRCh38)NC_000002.12_g.233760233_233760234insTATA
Allelic Frequency50%
ZygosityHeterozygous
  
Product Information 
Intended UseResearch Use Only
Unit Size1ug
ConcentrationDownload for COA
PuroficationDownload for COA
DNA electrophoresisDownload for COA
Sanger sequencing
Storage4°C
Expiry36 months from the date of manufacture