| pCBRG-FXRE |
| Cat.No.: | RQV20061 |
| Description: | pFXRE-Luc is designed for monitoring the induction of farnesoid X receptor.FXR is expressed at high levels in the liver and intestine. Chenodeoxycholic acid and other bile acids are natural ligands for FXR. Similar to other nuclear receptors, when activated, FXR translocates to the cell nucleus, forms a dimer (in this case a heterodimer with RXR) and binds to hormone response elements on DNA, which up- or down-regulates the expression of certain genes. |
| Plasmid profile: |  |
| Unit Size: | 1-4μg |
| Pathway (Activitor): | Farnesoid X Receptor |
| Pathway profile: |  |
| Full Name: | Farnesoid X Receptor |
| Cis response element: | FXRE |
| Shelf Life: | One year from date of receipt under proper storage conditions. |
| Storage: | -20°C |
| Mode of transportation: | Ice bag transport |
| Matters needing attention: | For your health, please wear lab clothes and disposable gloves. |
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