Detailed introduction

Panel-Ref^® Structural Variation Cocktail I-gDNA
Cat No.	RQP90033
Format	gDNA
Description	It is a mixture of structural variation sites, including SNV, Indel, DNA arrangement and CNV, with a total of 8 genes and 8 sites, all of which were calibrated by ddPCR.

General information
Gene	DNA Change	AA Change	Variant Type	AF	Cosmic ID	Chr position (GRCh37)
AKT1	c.49G>A	p.E17K	SNV	5%	COSM33765	chr14:105246551
PIK3CA	c.1624G＞A	p.E542K	SNV	5%	COSM760	chr3:178936082
ERBB2	c.2324_2325ins12	p.A775_G776insYVMA	Insertion	5%	COSM20959	chr17:37880995_37880996
EGFR	c.2235_2249del15	p.E746_A750delELREA	Deletion	5%	COSM6223	chr7:55242465_55242479
ROS1	N/A	CD74(E6)-ROS1(E34) Fusion	Fusion	5%	N/A	N/A
ALK	N/A	EML4(E13)-ALK(A20) Fusion V1	Fusion	5%	N/A	N/A
MET	N/A	MET Amplification	CNV	CN=5	N/A	N/A
ERBB2	N/A	ERBB2 Amplification	CNV	CN=5	N/A	N/A
NRAS	c.181C>A	p.Q61K	SNV	5%	COSM580	chr1:115256530
IDH1	c.394C>T	p.R132C	SNV	5%	COSM28747	chr2:209113113
Calibration method: DdPCR

Product Information
Intended Use	Research Use Only
Unit Size	1ug/vial * 1 vial
Concentration	Download for COA
Purity	Download for COA
DNA Electrophoresis	Download for COA
Storage	4℃
Expiry	36 months from the date of manufacture

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Panel-Ref® Structural Variation Cocktail I-gDNA