| Panel-Ref® FFPE All-in-One Reference Standard | |||||
| Cat No. | RQP90017 | ||||
| Format | FFPE Block | ||||
| Cell Number(2*10e8cells) | 2.19*10e8cells | ||||
| Description | Contains a variety of common genes, involving Mutation, Translocation, CNV, quality control products for clinical tumor-related detection. | ||||
| General information | |||||
| Gene | AA Change | Expected AF | DdPCR AF | NGS AF | Chr position (GRCh37) |
| EGFR | p.E746_A750delELREA | 7.50% | 7.50% | 6.82% | chr7:55242465_55242479 |
| EGFR | p.G719A | 5.00% | N/A | 5.42% | chr7:55241708 |
| EGFR | p.S768I | 5.00% | 5.32% | 6.33% | chr7:55249005 |
| EGFR | p.T790M | 10.00% | 11.80% | 10.02% | chr7:55249071 |
| EGFR | p.L858R | 10.00% | 9.70% | 8.81% | chr7:55259515 |
| ERBB2 | p.A775_G776insYVMA | 5.00% | N/A | 4.88% | chr17:37880995_37880996 |
| KRAS | P.G13D | 9.00% | 9.42% | 8.37% | chr12:25398281 |
| BRAF | p.V600E | 58.00% | 58.20% | 59.46% | chr7:140453136 |
| PIK3CA | p.H1047R | 50.00% | 51.20% | 50.92% | chr3:178952085 |
| BRCA1 | p.D435Y | 41.21% | N/A | 39.04% | chr17:41246245 |
| BRCA2 | p.Q1782fs | 35.00% | N/A | 31.70% | N/A |
| BRCA2 | p.I2675fs*6 | 10.00% | N/A | 11.21% | chr13:32937360 |
| CTNNB1 | p.S45del | 9.00% | N/A | 10.34% | chr3:41266136_41266138 |
| APC | p.K1454E | 41.21% | N/A | 40.13% | chr5:112175651 |
| FGFR2 | p.P582L | 7.69% | N/A | 9.37% | N/A |
| IDH2 | p.G190D | 41.21% | N/A | 42.29% | chr15:90631700 |
| Product Information | |||||
| Intended Use | Research Use Only | ||||
| Unit Size | 1 FFPE Slide | ||||
| Concentration | Download for COA | ||||
| Purity | Download for COA | ||||
| DNA Electrophoresis | Download for COA | ||||
| Storage | RT | ||||
| Expiry | 36 months from the date of manufacture | ||||
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