| Panel-Ref® gDNA Cocktail II Reference Standard | ||||||
| Cat No. | RQP90009 | |||||
| Description | Contains important loci of common genes, involving EGFR/BRAF/PIK3CA/ERBB2/KRAS and other genes | |||||
| Gene | AA change | CDS Change | Cosmic ID | Expected AF | %AF | Chr position (GRCh37) |
| EGFR | p.G719A | c.2156G>C | COSM6239 | 5.00% | 4.53% | chr7:55241708 |
| EGFR | p.L747_P753>S | c.2240_2257del | COSM12370 | 5.00% | 5.59% | chr7:55242470_55242487 |
| EGFR | p.V769_D770insASV | c.2307_2308insGCCAGCGTG | COSM12376 | 5.00% | 5.27% | chr7:55249010_55249011 |
| KRAS | p.G12C | c.34G>T | COSM516 | 5.00% | 4.53% | chr12:25398285 |
| KRAS | p.Q61H | c.183A>T | COSM555 | 5.00% | 5.68% | chr12:25380275 |
| KRAS | p.A146T | c.436G>A | COSM19404 | 5.00% | 5.54% | chr12:25378562 |
| ERBB2 | p.V777L | c.2329G>T | COSM14062 | 5.00% | 4.40% | chr17:37881000 |
| NRAS | p.G12C | c.34G>T | COSM562 | 5.00% | 5.33% | chr1:115258748 |
| NTRK1 | TPM3(E7)-NTRK1(E10) | N/A | N/A | 5.00% | 5.75% | N/A |
| ABL1 | BCR(E13)-ABL1(E2) | N/A | N/A | 5.00% | 5.28% | N/A |
| FGFR2 | CNV | N/A | N/A | 12 | CN=12.68 | N/A |
| MYC | CNV | N/A | N/A | 12 | CN=13.50 | N/A |
| Product Information | ||||||
| Intended Use | Research Use Only | |||||
| Unit Size | 1ug/vial * 1 vial | |||||
| Concentration | Download for COA | |||||
| Purity | Download for COA | |||||
| DNA electrophoresis | Download for COA | |||||
| Storage | 4°C | |||||
| Expiry | 36 months from the date of manufacture | |||||
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