BCR(E19)-ABL1(E2)_P230 Fusion

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 RQP20215R
FormatRNA
DescriptionPresence of a BCR-ABL1 fusion gene is necessary for the pathogenesis of CML. In up to 95% of cases, a t(9;22) (q34;q11) translocation results in the BCR-ABL1 fusion gene (Faderl et al. 1999). This translocation results in the Philadephia chromosome. In rare CML cases lacking the traditional t(9;22) translocation, other translocations result in the creation of the BCR-ABL1 fusion gene, which sometimes involve multiple chromosomes.
  
Technical Data 
Left GeneBCR
Left Breakpointchr22:23654023:+
Right GeneABL1
Right Breakpointchr9:133729451:+
Cosmic IDN/A
BufferRNase-free H2O
  
Product Information
Intended UseResearch Use Only
Unit Size1ug
ConcentrationDownload for COA
PurityDownload for COA
RNA electrophoresisDownload for COA
Sanger sequencing
Storage-80℃
Expiry12 months from the date of manufacture