| RQP73249 | |
| I. Introduction | |
Cell Line Name： | AXL (Gas6 Dependent)/BaF3 |
Host Cell: | BA/F3 |
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10%FBS+1ug/ml Human Gas6 |
Mycoplasma Status: | Negative |
| II.Background | |
| AXL (TYRO7) is a receptor tyrosine kinase that is overexpressed in various forms of cancer, including breast, prostate, colorectal, and non-small cell cancers. AXL overexpression has been shown to encourage tumor progression and metastasis and to decrease the anti-tumor immune response, making AXL an attractive candidate for anticancer therapies. | |
| III. Representative Data | |
1. Anti-proliferation assay
Figure . Anti-proliferation assay of three reference compounds on the AXL (Gas6 Dependent)/BaF3 Stable Cell Line. | |
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