C-C chemokine receptor type 1 (CCR8) is a G protein-coupled receptor member of the CC chemokine subfamily of
receptors. Following interaction with its specific chemokine ligands, like macrophage inflammatory protein 1 alpha
(MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), and monocyte
chemoattractant protein 3 (MCP-3), it triggers the onset of a process known as chemotaxis. GenScript’s human
CCR8-expressing stable subline is guaranteed to function properly in the calcium flux assay.

CHO

Functional assay for CCR8 receptor

Figure 1. Recombinant CCR8/CHO constitutively expressing CCR8.

Figure 2. CCL1 effect on CCR8/CHO clone 36.